Lack of C-erbB-2 protein expression in pulmonary carcinoid tumours.
Open Access
- 1 April 1991
- journal article
- research article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 44 (4) , 343
- https://doi.org/10.1136/jcp.44.4.343
Abstract
To determine if amplification of the C-erb-B2 proto-oncogene could be correlated with prognosis in carcinoid tumours, 49 pulmonary carcinoid tumours (26 typical, 23 atypical) were examined using a polyclonal antibody to the C-terminal peptide of the C-erb-B2 protein sequence. No C-erb-B2 gene product could be shown: the demonstration of C-erb-B2 does not seem to help, therefore, in determining diagnosis or prognosis in pulmonary carcinoid tumours.Keywords
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