EFFECT OF PENTAMIDINE ON THE GROWTH OFESCHERICHIA COLI
- 1 February 1957
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 73 (2) , 172-177
- https://doi.org/10.1128/jb.73.2.172-177.1957
Abstract
The growth in simple medium of E. coli strain K-12 is inhibited by pentamidine. This inhibition is overcome by glutamic acid or a-ketoglutaric acid in a competitive manner. A "sparing" of glutamic acid in the suppression of inhibition occurs with combinations of isoleucine and valine. Transamination in dried cells between glutamic acid and a-keto valine is inhibited by pentamidine.Keywords
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