A RIBONUCLEIC ACID FRACTION FROM RAT LIVER WITH TEMPLATE ACTIVITY
- 1 October 1963
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 50 (4) , 630-638
- https://doi.org/10.1073/pnas.50.4.630
Abstract
A RNA species with a nucleotide composition somewhat similar to that of DNA has been isolated from a crude rat liver nuclear preparation. This material is 100 times more effective than ribosomal RNA in stimulating the incorporation of leucine into protein by a cell-free preparation of E. coli. Its activity is not inhibited by the presence of a large excess of ribosomal RNA. RNA preparations from the cytoplasm show very little template activity.Keywords
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