ERYTHEMA ANNULARE CENTRIFUGUM COINCIDENT WITH EPSTEIN‐BARR VIRUS INFECTION IN AN INFANT

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Abstract
Hammar, H. (Department of Dermatology, Karolinska Sjukhuset, Stockholm, Sweden). Erythema annulare centrifugum coincident with Epstein‐Barr virus infection in an infant. Acta Paediatr Scand63: 788, 1974.—Persistent annular erythemas include various more or less distinctly defined clinical entities mostly found in adults but are sometimes seen in infants. Erythema annulare centrifugum is distinguished as one group among these dermatoses. The pathogenesis of the annular erythemas is not clearly understood. A two‐week‐old girl who developed recurrent erythema annulare centrifugum during her first 6 months of life is described. Significant changes in the titres of anti‐Epstein‐Barr virus antibodies were coincident with the clinical course. The general health of the girl was not affected and there were no signs of infectious mononucleosis either in the girl or in her mother. The eruption left an apparently normal skin except for one lesion with atrophy and telangiectases one year after its first appearance. The coincistence of the significant rise and fall of anti‐Epstein‐Barr antibody titres with the clinical appearance of erythema annulare centrifugum strongly suggests a pathogenetic effect of the virus on the skin eruption.

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