LYSOSOMAL AND ATP CHANGES AFTER RENAL-STALK CLAMPING IN RATS .1. PROTECTIVE ACTION OF TRASYLOL

  • 1 January 1977
    • journal article
    • research article
    • Vol. 4  (1) , 55-68
Abstract
The action of Trasylol on the lysosomal and ATP changes after renal-stalk clamping in rats was examined. In the presence of an effective Trasylol concentration, a distinct stabilization of the lysosomal membrane was detected after 30 min of renal-stalk clamping. There was only an indirect relationship between lysosomal changes and ATP metabolism under the action of Trasylol. The more rapid regeneration of the ATP was a result of the better microcirculation. The results confirm the earlier belief that Trasylol acts primarily on the lysosomal membrane.

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