Cobalt-catalyzed Cross-coupling Reaction of Chloropyridines with Grignard Reagents
- 28 August 2004
- journal article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 33 (10) , 1240-1241
- https://doi.org/10.1246/cl.2004.1240
Abstract
Treatment of 2-chloropyridine with benzylmagnesium chloride in the presence of a catalytic amount of cobalt(II) acetylacetonate in dioxane afforded the corresponding cross-coupling product in excellent yield. Trimethylsilylmethyl and phenyl Grignard reagents also participated in similar cross-coupling reactions.Keywords
This publication has 12 references indexed in Scilit:
- Cobalt-Catalyzed Allylic Substitution Reaction of Allylic Ethers with Phenyl and Trimethylsilylmethyl Grignard ReagentsChemistry Letters, 2004
- Cobalt-Catalyzed Arylation of Azole Heteroarenes via Direct C−H Bond FunctionalizationOrganic Letters, 2003
- Cobalt-Catalyzed Direct Electrochemical Cross-Coupling between Aryl or Heteroaryl Halides and Allylic Acetates or CarbonatesThe Journal of Organic Chemistry, 2002
- Cobalt-Catalyzed Coupling Reaction of Alkyl Halides with Allylic Grignard ReagentsAngewandte Chemie International Edition in English, 2002
- Iron-Catalyzed Cross-Coupling ReactionsJournal of the American Chemical Society, 2002
- Iron-Catalyzed Cross-Coupling Reactions of Alkyl-Grignard Reagents with Aryl Chlorides, Tosylates, and TriflatesAngewandte Chemie International Edition in English, 2002
- Cobalt-Catalyzed Tandem Radical Cyclization and Cross-Coupling Reaction: Its Application to Benzyl-Substituted HeterocyclesJournal of the American Chemical Society, 2001
- Cobalt-catalyzed alkenylation of zinc organometallicsTetrahedron Letters, 1998
- Cobalt-catalyzed alkenylation of organomagnesium reagentsTetrahedron Letters, 1998
- Factors Determining the Course and Mechanisms of Grignard Reactions. IV. The Effect of Metallic Halides on the Reaction of Aryl Grignard Reagents and Organic Halides1Journal of the American Chemical Society, 1941