INFECTIONS AND ANTIBIOTIC-PROPHYLAXIS IN THE FULGURATED RAT BLADDER

  • 1 January 1980
    • journal article
    • research article
    • Vol. 17  (4) , 277-283
Abstract
A model is described for establishing [Pseudomonas aeruginosa or Escherichia coli] infection in a fulgurated rat bladder. Persistence of bacteriuria was dependent on the size of the bacterial inoculum. Infection in an injured bladder exposed to a single predictable bacterial inoculum may be prevented by a single dose of antibiotic. The appropriate timing of antibiotic administration varies with the infecting organism.

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