Reductive activation of potential antitumor bis(aziridinyl)benzoquinones by xanthine oxidase: Competition between oxygen reduction and quinone reduction
- 1 February 1990
- journal article
- research article
- Published by Elsevier in Archives of Biochemistry and Biophysics
- Vol. 277 (1) , 137-142
- https://doi.org/10.1016/0003-9861(90)90561-c
Abstract
No abstract availableKeywords
This publication has 18 references indexed in Scilit:
- DNA alkylation and formation of DNA interstrand cross-links by potential antitumour 2,5-bis(1-aziridinyl)-1,4-benzoquinonesChemico-Biological Interactions, 1989
- Human drug metabolism in vitroPharmacology & Therapeutics, 1988
- Role of hydrogen peroxide in the cytotoxicity of the xanthine/xanthine oxidase systemBiochemical Journal, 1988
- Oxidation of reduced cytochrome c by hydrogen peroxideFEBS Letters, 1987
- Metabolism and reactions of quinoid anticancer agentsPharmacology & Therapeutics, 1987
- The role of mitomycin antibiotics in the chemotherapy of solid tumorsBiochemical Pharmacology, 1986
- Overview of enzyme systems involved in bioreduction of drugs and in redox cyclingBiochemical Pharmacology, 1986
- Interactions of anticancer quinone drugs, aclacinomycin A, adriamycin, carbazilquinone, and mitomycin C, with NADPH-cytochrome P-450 reductase, xanthine oxidase and oxygen.Journal of Pharmacobio-Dynamics, 1986
- Potential central nervous system antitumor agents. Aziridinylbenzoquinones. 2Journal of Medicinal Chemistry, 1976
- Antileukemic Agents. II. New 2, 5-Bis (1-aziridinyl)-p-benzoquinone DerivativesCHEMICAL & PHARMACEUTICAL BULLETIN, 1972