Antitubercular Dihydroagarofuranoid Sesquiterpenes from the Roots of Microtropis fokienensis
- 17 January 2007
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 70 (2) , 202-205
- https://doi.org/10.1021/np060500r
Abstract
Four new dihydroagarofuranoid sesquiterpenes (1−4) and a new hydroxybenzylsalicylaldehyde, forkienin (5), together with nine known compounds have been isolated from the roots of Microtropis fokienensis. The structures of the new compounds were determined through analyses of physical data. Compounds 3, 4, 7, and 8 exhibited potent antitubercular activities (MICs ≤ 26.0 μM) against Mycobacterium tuberculosis 90-221387 in vitro.Keywords
This publication has 5 references indexed in Scilit:
- A New Adjacent Bis-Tetrahydrofuran Annonaceous Acetogenin from the Seeds ofUvaria chamaePlanta Medica, 2006
- Xanthones from the Roots ofPolygala caudataand their Antioxidation and Vasodilatation Activitiesin vitroPlanta Medica, 2005
- Immunosuppressive Sesquiterpene Alkaloids from Tripterygium wilfordiiJournal of Natural Products, 2001
- Mutangin, a dihydroagarofuranoid sesquiterpene insect antifeedant from Elaeodendron buchananiiPhytochemistry, 1993
- Antitumour triterpenes of Maytenus diversifoliaPhytochemistry, 1986