Histological assessment of skin damage by irritants: its possible use in the evaluation of a ‘barrier cream’
- 1 August 1984
- journal article
- research article
- Published by Wiley in Contact Dermatitis
- Vol. 11 (3) , 179-185
- https://doi.org/10.1111/j.1600-0536.1984.tb00967.x
Abstract
The histological changes induced by topical application of selected irritants on guinea pigs are reported. The possible application of this methodology to the evaluation of the protective value of a silicone-containing barrier cream is discussed. Although this crude method only allows objectivity of the later stages of a toxic reaction, it gives useful information about the potential protective effect of a silicone-containing barrier cream.Keywords
This publication has 3 references indexed in Scilit:
- A Method for the Study of the Effect of Barrier Creams and Protective Gloves on the Percutaneous Absorption of SolventsDermatology, 1982
- The challenge of industrial dermatitisClinical and Experimental Dermatology, 1980
- The Influence of Two Barrier Creams on the Percutaneous Absorption of m-Xylene in ManJournal of Occupational and Environmental Medicine, 1978