THE VAGARIES OF ERYTHROLEUKAEMIA

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Abstract
A 10‐year material of erythroleukaemia from a department of medicine subspecialized in haematology is presented. A total of 14 cases fulfilled the following criteria for erythroleukaemia: erythroblastic hyperplasia of the bone marrow, either normo‐ or megaloblastic, ineffective erythropoiesis, no evidence of vitamin B12 or tolic acid deficiency, relatively few myeloblasts in the bone marrow in the initial stage, a lethal outcome and leukaemic infiltrates in later bone marrow aspirates and often in the organs at autopsy. The great variability in the clinical picture, in the morphology of the red blood cell precursors, and in the course of erythroleukaemia is emphasized, and the connection with other so‐called myeloproliferative disorders is illustrated by the common transformation to acute myeloid leukaemia and the development of erythroleukaemia from polycythaemia vera and chronic myeloid leukaemia.