Active site dynamics of toluene hydroxylation by cytochrome P-450
- 1 June 1990
- journal article
- research article
- Published by American Chemical Society (ACS) in The Journal of Organic Chemistry
- Vol. 55 (13) , 3992-3997
- https://doi.org/10.1021/jo00300a010
Abstract
No abstract availableThis publication has 19 references indexed in Scilit:
- The metabolism of 9-methylanthracene by rat-liver microsomal preparationsXenobiotica, 1986
- Intramolecular kinetic deuterium isotope effects on microsomal hydroxylation and chemical chlorination of toluene-.alpha.-d1 and toluene-.alpha.,.alpha.-d2Journal of the American Chemical Society, 1985
- Microsomal hydroxylation of specifically deuterated monosubstituted benzenes. Evidence for direct aromatic hydroxylationBiochemistry, 1984
- Kinetic isotope effects on cytochrome P-450-catalyzed oxidation reactions. Evidence for the irreversible formation of an activated oxygen intermediate of cytochrome P-448.Journal of Biological Chemistry, 1984
- Regioselectivity in the cytochromes P-450: Control by protein constraints and by chemical reactivitiesArchives of Biochemistry and Biophysics, 1984
- Isotope effects on the metabolism and pulmonary toxicity of butylated hydroxytoluene in mice by deuteration of the 4-methyl groupToxicology and Applied Pharmacology, 1983
- Phenobarbital-induced rat liver cytochrome P-450. Purification and characterization of two closely related isozymic forms.Journal of Biological Chemistry, 1982
- Metabolism of toluene in man: gas-chromatographic determination of o-, m- and p-cresol in urineArchives of Toxicology, 1979
- Secondary deuterium isotope effects on olefin epoxidation by cytochrome P-450Biochemical Pharmacology, 1978
- Aliphatic hydroxylation by highly purified liver microsomal cytochrome P-450. Evidence for a carbon radical intermediateBiochemical and Biophysical Research Communications, 1978