CIS-DICHLORODIAMMINEPLATINUM(II) IN METASTATIC SOFT-TISSUE SARCOMAS

  • 1 January 1979
    • journal article
    • research article
    • Vol. 63  (11-1) , 2071-2075
Abstract
Cis-Dichlorodiammineplatinum(II) was given to 13 patients with metastatic sarcomas following failure in all of them to 2 previous chemotherapy protocols. Two of these patients had complete regression which lasted 6 mo. in 1 patient and is still present after 8 mo. in the other. One patient had a > 50% regression which lasted 5 mo.. Three patients had disease stabilization for 2 mo. each. cis-Dichlorodiammineplatinum(II), as a single agent, was well-tolerated with no significant renal or auditory toxicity.