Membrane Sialic Acid and Behaviour in vivo of Rabbit “Stress” Macroreticulocytes

Abstract
Membranes of rabbit reticulocytes obtained by phenylhydrazine stimulation have a chemical composition different from that of normal erythrocytes; sialic acid/protein and cholesterol/protein ratios are lower than normal. In vivo study of 51Cr-labeled reticulocytes show that these cells are quickly removed from blood and, after a short homing in liver, return to peripheral blood. During homing in the liver, the sialic acid/protein ratio seems to increase.

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