Intermittent myelination of small-diameter sciatic axons inXenopus laevis

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Abstract
Nerve fibres from the sciatic nerve of apparently normalXenopus laevis were examined in teased preparations of living material and in series of cross-sections. Small-diameter fibres were found that were myelinated in a spatially intermittent fashion. In these fibres, the myelinated segments were separated by long non-myelinated regions that had a 1 ∶ 1 relationship to the investing Schwann cell. It is estimated that at least 10% of the myelinated fibres with an external diameter of less than 5 μm were intermittently myelinated.