A QUANTITATIVE LIGHT-MICROSCOPIC AND ELECTRON-MICROSCOPIC STUDY OF TYPE-IV NUCLEAR-BODIES IN CRESCENTIC GLOMERULONEPHRITIS

  • 1 January 1981
    • journal article
    • research article
    • Vol. 102  (3) , 359-366
Abstract
Type IV nuclear bodies were found in all renal biopsies obtained from 14 patients with crescentic glomerulonephritis (CGN), and in 8 of 43 control patients studied by light microscopy and EM. The mean ratio of Type IV nuclear bodies/100 tubular cross-sections examined was 0.67 .+-. 0.27 for the CGN cases, which was significantly different from 0.09 .+-. 0.26 obtained for the controls (P < 0.05). Type IV nuclear bodies were most commonly seen in the epithelial cells of proximal tubules, but were also seen occasionally in interstitial fibroblasts and cells of a collecting duct and a developing crescent.