Elongation factor EF-1 alpha gene dosage alters translational fidelity in Saccharomyces cerevisiae.
Open Access
- 1 October 1989
- journal article
- research article
- Published by Taylor & Francis in Molecular and Cellular Biology
- Vol. 9 (10) , 4571-4575
- https://doi.org/10.1128/mcb.9.10.4571
Abstract
Changes in the dosage of genes encoding elongation factor EF-1 alpha were shown to cause parallel changes in the misreading of nonsense codons. Higher amounts of EF-1 alpha were correlated with increased nonsense suppression, suggesting that the level of EF-1 alpha is critically involved in translational fidelity.This publication has 36 references indexed in Scilit:
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