Electron Microscopic Localization of Virions in Developing Teeth of Young Hamsters Infected With Minute Virus of Mice
- 1 January 1980
- journal article
- research article
- Published by SAGE Publications in Journal of Dental Research
- Vol. 59 (1) , 80-86
- https://doi.org/10.1177/00220345800590011501
Abstract
Virus particles were detected within the nuclei and cytoplasm of odontogenic cells in the developing teeth of young hamsters infected with a small DNA virus (MVM). Disturbances of normal cytodifferentiation and organogenesis occurred as a result of viral multiplication. Virions were also observed in dense lysosome-like bodies of activated monocytes within the periodontal ligament and adjacent connective tissues. Fibrolytic and osteolytic lesions in the periodontal ligament and adjacent alveolar bone were associated with the inflammatory cell infiltrate.This publication has 18 references indexed in Scilit:
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