Tumour Lysis Syndrome with Hypocalcaemia in Accelerated Chronic Granulocytic Leukaemia

Abstract
Tumour lysis syndrome is a well-known complication of lymphoid malignancies, but it has rarely been described in myeloproliferative disorders. A patient is reported with myeloblastic type of accelerated chronic granulocytic leukaemia who developed a tumour lysis syndrome following intensive chemotherapy. The most prominent manifestation of such a syndrome was hypocalcaemia, which was associated with other biochemical alterations, including hyperphosphataemia, hyperuricaemia and renal failure.

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