Minocycline-induced Lupus in Adolescents

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Abstract
The patients were girls ranging in age from 14 to 17 years who were referred to the pediatric rheumatology clinic at the Floating Hospital for Children by their primary pediatricians because of suspected lupus or other rheumatic disease. Drug exposures were sought during routine history taking. Serologic tests were performed at the New England Medical Center using standard methods. Antihistone antibodies were assayed at a commercial laboratory (Smithkline Beecham, Framingham, MA).