Effect of Chelating Agent on Urinary Lead Excretion. Comparison of Oral and Intravenous Administration
- 1 February 1953
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 82 (2) , 226-228
- https://doi.org/10.3181/00379727-82-20073
Abstract
Di-Na Ca ethylenediaminetetraacetate was given intraven., orally or alternately by both routes to 7 patients with elevated blood Pb and/or urinary Pb excretion. The oral dose was 30 mg./kg. twice daily. Intraven. dosage in adults was 1.0 g. on the 1st day and 2.0 g. for 4 days given in divided doses diluted to 250 ml. with 5% glucose in water. A 5- to 60-fold increment in urinary lead excretion was effected. Intraven. therapy was more effective than oral. No untoward side-reactions were encountered with the dosage indicated.Keywords
This publication has 1 reference indexed in Scilit:
- Experimental Control of Serum Calcium Levels in Vivo.Experimental Biology and Medicine, 1950