High-performance liquid chromatographic method for the direct determination of 4-methylumbelliferone and its glucuronide and sulfate conjugates: Application to studies in the single-pass in situ perfused rat intestine—liver preparation
- 18 January 1991
- journal article
- Published by Elsevier in Journal of Chromatography B: Biomedical Sciences and Applications
- Vol. 563 (1) , 83-94
- https://doi.org/10.1016/0378-4347(91)80279-l
Abstract
No abstract availableKeywords
This publication has 10 references indexed in Scilit:
- Membrane-limited hepatic transport of the conjugative metabolites of 4‐methylumbelliferone in ratsJournal of Pharmaceutical Sciences, 1988
- Kinetics of hepatic transport of 4-methylumbelliferone in rats. Analysis by multiple indicator dilution methodJournal of Pharmacokinetics and Biopharmaceutics, 1987
- Conjugative metabolism of 4-methylumbelliferone in the rat liver: Verification of the sequestration process in multiple indicator dilution experiments.CHEMICAL & PHARMACEUTICAL BULLETIN, 1987
- Sublobular distribution of transferases and hydrolases associated with glucuronide, sulfate and glutathione conjugation in human liverHepatology, 1986
- Glucuronidation and sulfation in the rat in vivoBiochemical Pharmacology, 1985
- High-rate intestinal conjugation of 4-methylumbelliferone during intravenous infusion in the ratBiochemical Pharmacology, 1984
- Rapid high-performance liquid chromatographic method for the measurement of hymecromon and its conjugates in blood plasma or serum at concentrations attained during therapyJournal of Chromatography B: Biomedical Sciences and Applications, 1983
- Glucuronide and sulphate conjugation in isolated liver cells from control and phenobarbital- or PCB-treated ratsBiochemical Pharmacology, 1980
- Hepatic clearance of drugs. II. Experimental evidence for acceptance of the “well-stirred” model over the “parallel tube” model using lidocaine in the perfused rat liverin situ preparationJournal of Pharmacokinetics and Biopharmaceutics, 1977
- Quantitative determination of phenolsulfotransferase using 4-methylumbelliferoneAnalytical Biochemistry, 1972