Brønsted acid catalysed electrophilic substitution of indole by allylic alcohols in lithium perchlorate–diethyl ether: application to the total synthesis of yuehchukene
- 1 January 1993
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 6,p. 510-512
- https://doi.org/10.1039/c39930000510
Abstract
A novel carbon–carbon bond-forming reaction between indole and ββ-disubstituted allylic alcohols in lithium perchlorate–diethyl ether containing a catalytic amount of a Brønsted acid is described; the reaction has been applied to a total synthesis of yuehchukene.Keywords
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