Urinary Modified Nucleosides as Tumor Markers
- 1 October 2003
- journal article
- Published by Taylor & Francis in Nucleosides, Nucleotides and Nucleic Acids
- Vol. 22 (5-8) , 987-989
- https://doi.org/10.1081/ncn-120022719
Abstract
Extracts of urinary nucleosides have been sequentially purified and examined by mass spectrometric analysis. Seventeen modified nucleosides have been unequivocally identified and a further five provisionally identified. While several nucleosides were found only in a small number of extracts, the occurrence and levels of others were found to correlate with the tumour type and stage.Keywords
This publication has 3 references indexed in Scilit:
- Analysis of urinary nucleosides. II. Comparison of mass spectrometric methods for the analysis of urinary nucleosidesRapid Communications in Mass Spectrometry, 2001
- Analysis of urinary nucleosides. I. Optimisation of high performance liquid chromatography/electrospray mass spectrometryRapid Communications in Mass Spectrometry, 2000
- Development of a Purification Procedure for the Isolation of Nucleosides from Urine Prior to Mass Spectrometric AnalysisNucleosides, Nucleotides and Nucleic Acids, 2000