PROSTAGLANDINS-E AND PROSTAGLANDIN-F IN THE UTERINE TISSUE OF CYCLIC RATS

  • 1 January 1979
    • journal article
    • research article
    • Vol. 24  (2) , 130-133
Abstract
Prostaglandins E and F (PGE and PGF) levels and the biosynthetic ability of rat uterine tissue were estimated in the various phases of estrus cycle by radioimmunoassay technique. Significantly high PGF concentration was found during metestrus phase. In comparison, PGE levels did not show as high an elevation. The metestrus phase also showed significantly higher biosynthesis of prostaglandins E and F. The role of prostaglandins in ovulation and luteolysis of the corpus luteum is supported.