FUCOSE INCORPORATION INTO RAT HIPPOCAMPUS STRUCTURES AFTER ACQUISITION OF A BRIGHTNESS-DISCRIMINATION - HISTOAUTORADIOGRAPHIC ANALYSIS

  • 1 January 1979
    • journal article
    • research article
    • Vol. 38  (1) , 53-63
Abstract
Using a brightness discrimination model in rats, the labeling of discrete hippocampus formation structures was studied after intraventricular application of [3H]fucose. This substance was injected 5 min before training and 5 min, 3, 7 and 23 h after training, the pulse period lasting 120 min in all cases. A significantly training-related enhanced labeling of CA1, CA3 and CA4 cell bodies and fibers revealed that a biphasic time course occurr when [3H]fucose was applied 5 min before training and 7 h after training, whereas the increased labeling of area dentata structures was evidenced only after application of radioactive fucose 5 min before and after training. In all structures under investigation the training-related increase in labeling was more pronounced in the fiber layers than in the pyramidal and granular cell bodies.