Expression of Dipeptidylaminopeptidase-IV in Some Human T and B Cell Lines
- 1 January 1986
- journal article
- research article
- Published by S. Karger AG in Acta Haematologica
- Vol. 76 (1) , 25-28
- https://doi.org/10.1159/000206013
Abstract
The specificity of the expression of dipeptidylaminopeptidase-IV (DAP-IV) was examined in cells from leukemia patients and in 33 normal and leukemic human cell lines widely used in various studies. There was no correlation between DAP-IV activity and OKT4 positivity or maturation stage in T cells. In addition, DAP-IV was unexpectedly expressed by 4 B cell lines and 1 histiocytic lymphoma cell line, indicating either lack of specificity of DAP-IV or infidelity of gene expression under unnatural culture environment.Keywords
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