Expression of 20α‐hydroxysteroid dehydrogenase in nonlymphoid hemopoietic cell lines
- 1 January 1982
- journal article
- research article
- Published by Wiley in European Journal of Immunology
- Vol. 12 (4) , 332-336
- https://doi.org/10.1002/eji.1830120414
Abstract
Expression of 20α‐hydroxysteroid dehydrogenase (20α‐SDH), a putative T cell marker. has been examined in a number of nonlymphoid hemopoietic cell lines. Both promyelocytic and stromal bone marrow lines expressed significant 20α‐SDH activity which was not correlated with virus infection or growth rate. 20α‐SDH therefore is not a unique marker for T cells in hemopoietic tissues. This result is discussed in relationship to the action of the newly proposed interleukin 3.Keywords
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