Sedimentation and diffusion of human albumins. 2. Nephrotic human albumins at a low concentration

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Abstract
The albumin fractions of nephrotic sera and urine samples were isolated electro-phoretically. Sedimentation constants for these prepns. in the concn. range 0.2-0.3% agreed with detns. previously made on normal human albumins. In the Gouy diffusiometer the nephrotic serum albumins generally diffused more slowly, and the urinary albumins more rapidly, than normal. It was demonstrated that nephrotic albumins are abnormal. Probably the mean molecular wts. of nephrotic serum and urinary albumins are, resp., higher and lower than normal.