Recent Developments in the Understanding of the Pathogenesis and Treatment of Anaerobic Infections

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Abstract
(Second of Two Parts)Another clinical syndrome for which a putative anaerobic pathogen has been tentatively identified is nonspecific vaginitis, now often referred to as anaerobic vaginosis. In the past this condition was thought to be caused by Gardnerella vaginalis, but more recently by abnormal anaerobic vaginal flora, on the basis of culture results and an increased ratio of succinate to lactate in vaginal specimens.158 , 159 Several observers have found curved, motile anaerobic bacilli in association with this disease.160 161 162 163 164 165 166 These organisms have been assigned to the genus mobiluncus.167 Treatment with ampicillin or metronidazole has resulted in the clearance of these . . .