Monoclonal cytolytic T-cell lines.
Open Access
- 1 January 1979
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 149 (1) , 273-278
- https://doi.org/10.1084/jem.149.1.273
Abstract
Monospecific cloned cytolytic T[thymus derived]-lymphocyte lines [from mice] were created utilizing T-cell growth factor. The clones retained their cytolytic specificity after prolonged culture and monospecific function was demonstrated by subcloning procedures. Detailed studies of the phenotypic and functional characteristics of monospecific, homogeneous, cytolytic T [thymus-derived] lymphocytes will be possible.This publication has 7 references indexed in Scilit:
- Cloned T-Cell Lines with Specific Cytolytic ActivityPublished by Springer Nature ,1979
- Long-term culture of human antigen-specific cytotoxic T-cell lines.The Journal of Experimental Medicine, 1978
- T Cell Growth Factor: Parameters of Production and a Quantitative Microassay for ActivityThe Journal of Immunology, 1978
- Clones of alloreactive T cellsNature, 1978
- In vitro generation of tumor-specific cytotoxic lymphocytes. Secondary allogeneic mixed tumor lymphocyte culture of normal murine spleen cellsThe Journal of Experimental Medicine, 1977
- Long term culture of tumour-specific cytotoxic T cellsNature, 1977
- Independent differentiative pathways of Ly1 and Ly23 subclasses of T cells. Experimental production of mice deprived of selected T-cell subclasses.The Journal of Experimental Medicine, 1976