Synthesis of enantiomerically pure cis and trans 2-aminocyclopentanecarboxylic acids. Use of proline replacements in potential HIV-protease inhibitors
- 1 June 1997
- journal article
- Published by Elsevier in Tetrahedron
- Vol. 53 (23) , 7975-7984
- https://doi.org/10.1016/s0040-4020(97)00482-1
Abstract
No abstract availableKeywords
This publication has 29 references indexed in Scilit:
- Potent, orally bioavailable HIV-1 protease inhibitors containing noncoded D-amino acidsBioorganic & Medicinal Chemistry Letters, 1995
- Ly316340: A potent HIV-1 protease inhibitor containing a high affinity octahydrothienopyridine hydroxyethylamine isostereBioorganic & Medicinal Chemistry Letters, 1995
- Novel HIV01 protease inhibitors containing A β-hydroxy sulfide isostere.Bioorganic & Medicinal Chemistry Letters, 1994
- Inhibitors of HIV proteinaseExpert Opinion on Investigational Drugs, 1994
- Asymmetric synthesis of (–)-(1R,2S)-cispentacin and related cis- and trans-2-amino cyclopentane- and cyclohexane-1-carboxylic acidsJournal of the Chemical Society, Perkin Transactions 1, 1994
- Synthesis of Enantiomerically Pure trans-3,4-Substituted Cyclopentanols by Enzymatic Resolution.Acta Chemica Scandinavica, 1992
- HIV protease: a novel chemotherapeutic target for AIDSJournal of Medicinal Chemistry, 1991
- Rational Design of Peptide-Based HIV Proteinase InhibitorsScience, 1990
- Organic Reactions at Alumina SurfacesAngewandte Chemie International Edition in English, 1978
- Organic reactions at alumina surfaces. Mild and selective opening of epoxides by alcohols, thiols, benzeneselenol, amines, and acetic acidJournal of the American Chemical Society, 1977