Black pepper [pipernigrum]: Evidence of carcinogenicity
- 1 March 1979
- journal article
- other
- Published by Taylor & Francis in Nutrition and Cancer
- Vol. 1 (3) , 22-26
- https://doi.org/10.1080/01635587909513624
Abstract
An extract of black pepper was applied cutaneously to albino Swiss mice of both sexes; each animal received a total of 28 mg over a three‐month period. All pepper‐treated mice surviving after 17 months developed tumors, particularly in the lung, liver, and skin (distant from the area of application). The incidence of malignant tumors and of multiple tumors was significantly greater in the pepper‐treated mice than in the vehicle‐treated controls.Keywords
This publication has 20 references indexed in Scilit:
- Regeneration of rat liver in the presence of essential oils and their componentsFood and Cosmetics Toxicology, 1977
- Tumors in control mice: Literature tabulationToxicology and Applied Pharmacology, 1974
- Metabolism of Alkenebenzene Derivatives in the Rat I.p-Methoxyallylbenzene (Estragole) andp-Methoxypropenylbenzene (Anethole)Xenobiotica, 1973
- VOLATILE COMPOSITION OF BLACK PEPPERJournal of Food Science, 1971
- Food flavourings and compounds of related structure. II. Subacute and chronic toxicityFood and Cosmetics Toxicology, 1967
- Ultraviolet Spectra of AlkaloidsChemical Reviews, 1965
- Chronic toxicity of essential oils and certain other products of natural originFood and Cosmetics Toxicology, 1965
- Toxic properties of compounds related to safroleToxicology and Applied Pharmacology, 1965
- 241. Piperettine from Piper nigrum; its isolation, identification, and synthesisJournal of the Chemical Society, 1950
- Natürliche und künstliche Pfefferstoffe, II.: Über das Chavicin des Pfefferharzes, den vorzugsweise wirksamen Bestandteil des schwarzen Pfeffers. (Mitbearbeitet von Otto Lüdemann und Heinrich Heimann)Berichte der deutschen chemischen Gesellschaft (A and B Series), 1922