Iatrogenous Cocaine Psychosis

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Abstract
To the Editor: It has been suggested that cocaine, a local anesthetic and a Central-nervous-system stimulant,1 may provoke a paranoid schizophreniform psychosis similar to that associated with amphetamines,2 when used for a long time or in high doses.3 , 4 This toxic syndrome is characterized by paranoia; inability to concentrate; restlessness; vivid visual, auditory, and tactile hallucinations, with delusions of parasitosis; and a stereotyped compulsive repetitive behavior — all with a clear sensorium.3 4 5 To date, these phenomena have been reported only by recreational cocaine users and have not been observed in a controlled laboratory setting.5 We observed an iatrogenous cocaine psychosis . . .

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