Somatic Cell Mating and Segregation in Chimeric Frogs
- 15 May 1970
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 168 (3933) , 850-852
- https://doi.org/10.1126/science.168.3933.850
Abstract
Both pentaploid and haploid cells were observed in a short-term culture of bone marrow of a diploid-triploid frog chimera. Apparently, diploid and triploid marrow cells fused to form "hybrid" pentaploid cells, which subsequently gave rise by somatic reduction to haploid daughter cells. The hybrid marrow cells and their haploid segregants are presumably at a selective disadvantage, as neither type of cell has been detected in the circulating blood of chimeric frogs.Keywords
This publication has 14 references indexed in Scilit:
- Chromosomal distribution in interspecific in vitro hybrid cellsExperimental Cell Research, 1968
- Germ Cell Chimerism: Absence in Parabiotic FrogsScience, 1968
- Spontaneous occurrence of tetraploidy and near-haploidy in mammalian peripheral bloodExperimental Cell Research, 1967
- Evidence from Cultured Leucocytes of Blood Cell Chimerism in Ex-Parabiotic FrogsScience, 1966
- A Selective System for the Isolation of Hybrids Between L Cells and Normal CellsNature, 1965
- Hybridization of Normal and Neoplastic Cells in vitroNature, 1965
- The Selection of Hybrid Mouse FibroblastsCold Spring Harbor Symposia on Quantitative Biology, 1964
- Chromosome preparations of leukocytes cultured from human peripheral bloodExperimental Cell Research, 1960
- SEGREGATION AND REDUCTION IN SOMATIC TISSUESJournal of Heredity, 1948
- Immunogenetic Consequences of Vascular Anastomoses Between Bovine TwinsScience, 1945