The biosynthesis of citrinin by Penicillium citrinum
- 1 January 1981
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 9,p. 2577-2583
- https://doi.org/10.1039/p19810002577
Abstract
Incorporation studies have been carried out with [Me-13C]methionine and aromatic compounds labelled with 14C or 2H. Evidence is presented that 4,6-dihydroxy-3,5-dimethyl-2-(1-methyl-2-oxopropyl)benzaldehyde (13) is the first enzyme-free aromatic intermediate in the biosynthesis of citrinin in P. citrinum, and that all three methylations take place on the polyketide synthetase complex.This publication has 6 references indexed in Scilit:
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- Streptonigrin biosynthesis. 3. Determination of the primary precursors to the 4-phenylpicolinic acid portionJournal of the American Chemical Society, 1980
- New insights into polyketide metabolism; the use of protium as a tracer in the biosynthesis of citrinin by Penicillium citrinumJournal of the Chemical Society, Perkin Transactions 1, 1980
- Biosynthesis of citrinin in Penicillium citrinum: advanced precursor studies using 2H nuclear magnetic resonance spectroscopyJournal of the Chemical Society, Chemical Communications, 1980
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- BIOGENESIS OF CITRININ1958