Genetic Length of a Human Chromosomal Segment Measured by Recombination Between Two Fragile Sites
- 23 July 1982
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 217 (4557) , 373-374
- https://doi.org/10.1126/science.7089572
Abstract
Two families were studied in which the same homolog of chromosome pair 10 expressed both the fragile sites on the long (q) arm at 10q23 and 10q25. Recombination between the fragile sites was observed in 3 of the 27 offspring in whom it could occur. The genetic length of chromosome between the fragile sites was 11 female centimorgans within a 95 percent probability interval of 4 to 28 centimorgans. This estimate of genetic length is comparable to those obtained with other methods.This publication has 5 references indexed in Scilit:
- Title Page / Table of ContentsCytogenetic and Genome Research, 1981
- Exclusion mapping illustrated by the MNSs blood groupAnnals of Human Genetics, 1980
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- Heritable Fragile Site on Chromosome 16: Probable Localization of Haptoglobin Locus in ManScience, 1970