Subtyping of Properdin Factor B (Bf) by Isoelectrofocusing
- 31 December 1981
- journal article
- research article
- Published by S. Karger AG in Human Heredity
- Vol. 32 (5) , 362-366
- https://doi.org/10.1159/000153323
Abstract
Properdin factor B (Bf) is a polymorphic protein in the human plasma. Two common alleles, BfS, BfF, and two rare alleles, BfF1, BfS1, have been demonstrated in Caucasians. We now report that BfF can be subtyped into two alleles, BfFa and BfFb by isoelectrofocusing. Family studies indicate that they are inherited in a co-dominant pattern. Gene frequencies for Caucasians are: BfS0.808, BfF1 0.019, Bfs1 0.005, Bfs1 0.038 and BfFa 0.128.Keywords
This publication has 7 references indexed in Scilit:
- GENETIC MARKER FOR INSULIN-DEPENDENT DIABETES MELLITUSThe Lancet, 1979
- Analysis of the Gc polymorphism in human populations by isoelectrofocusing on polyacrylamide gels. Demonstration of subtypes of the Gc1 allele and of additional Gc variantsHuman Genetics, 1978
- A new rare phenotype of glycine-rich ?-glycoproteinHuman Genetics, 1978
- Bf polymorphism: Another variant (S0.8)Human Genetics, 1977
- α1-Antitrypsin: Common Subtypes of Pi MHuman Heredity, 1976
- The Localization of the Bf Locus within the MHS Region on Chromosome No. 6Tissue Antigens, 1976
- PROPERDIN FACTOR-B (GLYCINE-RICH BETA-GLYCOPROTEIN OR C3 PROACTIVATOR)-POLYMORPHISM - GENETIC AND BIOCHEMICAL ASPECTS FIRST APPLICATION TO PATERNITY CASES1975