Inability of Plasmodium Knowlesi Sporozoites to Invade Anopheles Freeborni Salivary Glands
- 1 July 1985
- journal article
- research article
- Published by American Society of Tropical Medicine and Hygiene in The American Journal of Tropical Medicine and Hygiene
- Vol. 34 (4) , 687-691
- https://doi.org/10.4269/ajtmh.1985.34.687
Abstract
Oocysts of Plasmodium knowlesi developed normally on the gut of the mosquito Anopheles freeborni, rupturing and releasing sporozoites at 10–14 days post-infection. Subsequently, however, sporozoites were never found in this mosquito's salivary glands. Heterologous transplants of whole salivary glands from uninfected An. freeborni and An. dirus, a completely susceptible mosquito, into the abdomens of insects heavily infected with mature oocysts were done. Sporozoites failed to infect An. freeborni glands implanted in An. dirus but did enter An. dirus glands implanted in An. freeborni. These experiments suggest that P. knowlesi sporozoites are unable to recognize An. freeborni glands.This publication has 6 references indexed in Scilit:
- The protective antigen of malarial sporozoites (Plasmodium berghei) is a differentiation antigen.The Journal of Immunology, 1981
- Interaction between cytochalasin B-treated malarial parasites and erythrocytes. Attachment and junction formation.The Journal of Experimental Medicine, 1979
- Malaria immunization in Rhesus monkeys. A vaccine effective against both the sexual and asexual stages of Plasmodium knowlesi.The Journal of Experimental Medicine, 1978
- Studies on the Transmission of Simian Malarias II. Transmission of the H Strain of Plasmodium knowlesi by Anopheles balabacensis balabacensisJournal of Parasitology, 1967
- Electron Microscopic and Histochemical Studies of Sporozoite Formation in Plasmodium berghei*The Journal of Protozoology, 1967
- A Stain for Malarial Oocysts in Temporary PreparationsJournal of Parasitology, 1950