Predicting the severity of rhesus alloimmunization: monocyte‐mediated chemiluminescence versus maternal anti‐D antibody estimation
- 1 September 1994
- journal article
- Published by Wiley in British Journal of Haematology
- Vol. 88 (1) , 199-200
- https://doi.org/10.1111/j.1365-2141.1994.tb04998.x
Abstract
Anti-D haemolytic antibody concentration and chemiluminescence (CLT) opsonic index was measured in maternal blood obtained from 20 alloimmunized pregnancies at 17-28 weeks undergoing intrauterine fetal blood sampling for the estimation of fetal haemoglobin concentration. The fetal haemoglobin concentration was significantly associated with the maternal serum CLT opsonic index (r = -0.566, P < 0.01) but not with the maternal anti-D concentration (r = -0.329). The data of this study indicate that measurement of maternal serum CLT opsonic index may be more accurate than anti-D quantification in providing non-invasive prediction of the degree of fetal anaemia.Keywords
This publication has 3 references indexed in Scilit:
- Predicting hemolytic disease of the newborn: a comparison of the monocyte monolayer assay and the chemiluminescence testTransfusion, 1993
- Maternal serum anti-D antibody concentration and assessment of rhesus isoimmunisation.BMJ, 1992
- Correlation of serological, quantitative and cell‐mediated functional assays of maternal alloantibodies with the severity of haemolytic disease of the newbornBritish Journal of Haematology, 1991