Superactivity and dual reactivity of the system N-iodosuccinimide-H2SO4 in the iodination of deactivated arenes
- 1 September 2007
- journal article
- Published by Pleiades Publishing Ltd in Russian Journal of Organic Chemistry
- Vol. 43 (9) , 1278-1281
- https://doi.org/10.1134/s1070428007090035
Abstract
Dissolution of N-iodosuccinimide in sulfuric acid gives rise to electrophilic iodine-containing species which are capable of successfully iodinating aromatic compounds with electron-withdrawing substituents in the temperature range from 0 to 20°C. The iodination in sulfuric acid is effected by both protonated N-iodosuccinimide and IOS(O)(OH+)OH intermediate.Keywords
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