Extrapore Residues of the S5-S6 Loop of Domain 2 of the Voltage-Gated Skeletal Muscle Sodium Channel (rSkM1) Contribute to the μ-Conotoxin GIIIA Binding Site
Open Access
- 1 July 1998
- journal article
- research article
- Published by Elsevier in Biophysical Journal
- Vol. 75 (1) , 236-246
- https://doi.org/10.1016/s0006-3495(98)77510-1
Abstract
No abstract availableKeywords
Funding Information
- University of Pennsylvania
- National Institutes of Health (AR41,762)
- Heart And Stroke Foundation Of Quebec
- American Heart Association
- Medical Research Council Canada (MT-12554)
- Muscular Dystrophy Association
This publication has 39 references indexed in Scilit:
- Interactions between a Pore-Blocking Peptide and the Voltage Sensor of the Sodium Channel: An Electrostatic Approach to Channel GeometryNeuron, 1996
- The charybdotoxin family of K+ channel-blocking peptidesNeuron, 1995
- Structural determinants of the blockade of N-type calcium channels by a peptide neurotoxinNature, 1994
- The charybdotoxin receptor of a Shaker K+ channel: Peptide and channel residues mediating molecular recognitionNeuron, 1994
- Chimeric study of sodium channels from rat skeletal and cardiac muscleFEBS Letters, 1992
- Action of derivatives of .mu.-conotoxin GIIIA on sodium channels. Single amino acid substitutions in the toxin separately affect association and dissociation ratesBiochemistry, 1992
- Calcium channel characteristics conferred on the sodium channel by single mutationsNature, 1992
- Mapping the site of block by tetrodotoxin and saxitoxin of sodium channel IIFEBS Letters, 1991
- Disulfide pairings in geographutoxin I, a peptide neurotoxin from Conus geographusFEBS Letters, 1990
- A single point mutation confers tetrodotoxin and saxitoxin insensitivity on the sodium channel IIFEBS Letters, 1989