A Study of Illness in a Group of Cleveland Families

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Abstract
THE continuing development and improvement of tissue-culture methods have simplified the study of infectious agents, such as poliomyelitis1 , 2 and Coxsackie3 viruses, originally isolated in animal hosts, and have made possible the primary isolation of previously unidentified viruses.4 5 6 7 Of the last group, some, often referred to as "orphan" viruses, have not yet been related clearly to disease6 , 7; others, variously designated as the adenoidal-degeneration (AD), respiratory-infection (RI), acute-respiratory-disease (ARD) or adenoidal-pharyngeal-conjunctival (APC) group of viruses,4 , 5 , 8 9 10 11 have been related etiologically to certain respiratory diseases.8 9 10 11 12 13 Interest in this new group of respiratory viruses prompted a study of their role in the causation of . . .

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