Abstract
ON November 7, 1985, the Journal published the results of a randomized trial of extracranial–intracranial (EC–IC) arterial bypass surgery to reduce the risk of ischemic stroke in patients with symptomatic atherosclerotic disease of the internal carotid artery. 1 , 2 The trial was a major international effort, involving 71 neurosurgical centers all over the world and 1377 patients who were randomly assigned to medical or surgical treatment and followed for an average of more than 4 1/2 years. The study took eight years to complete and cost the U.S. National Institutes of Health (the National Institute of Neurological and Communicative Disorders and Stroke), . . .

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