Choice of ascertainment model I
- 1 October 1978
- journal article
- research article
- Published by Wiley in Annals of Human Genetics
- Vol. 42 (2) , 219-229
- https://doi.org/10.1111/j.1469-1809.1978.tb00654.x
Abstract
A statistical method for choosing between ascertainment models for human family data was constructed. The families were assumed to be ascertained through a single proband each and the birth number of the proband among the affected children is recorded. If the proband is the eldest affected child in each family the so-called complete ascertainment model has to be used. If each affected child has the same probability of being the proband, the single ascertainment model should be used. In intermediate cases a 3rd ascertainment model should be used.This publication has 18 references indexed in Scilit:
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