Lower Limb Paralysis Induced in Mice by a Temperature-Sensitive Mutant of Moloney Leukemia Virus2

Publisher Website
Google Scholar
Abstract
A temperature-sensitive mutant of Moloney murine leukemia virus defective in an early function and injected into newborn mice produced lower limb paralysis. Susceptible mice were inbred strains CFW/D, CBA/H, C3H/Bi/Ka, and outbred NIH Swiss stock. Inbred W/Fu rats and C57BL/Ka mice did not develop the paralysis, though the latter were infected with the virus; the sera from these mice produced paralysis in susceptible CFW mice.