Perinatal Exposure to Cannabinoids Alters Male Reproductive Function in Mice
- 28 September 1979
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 205 (4413) , 1420-1422
- https://doi.org/10.1126/science.472762
Abstract
Oral administration of Δ 9 -tetrahydrocannabinol or cannabinol to female mice late in pregnancy and during early lactation alters body weight regulation and pituitary-gonadal function and suppresses adult copulatory activity in their male offspring. These findings suggest that both psychoactive and nonpsychoactive constituents of marihuana can affect the development of male reproductive functions in mice.Keywords
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