Estrogen Formation by the Isolated Perfused Rhesus Monkey Brain
- 8 June 1973
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 180 (4090) , 1074-1075
- https://doi.org/10.1126/science.180.4090.1074
Abstract
Perfusion of two isolated brains from immature male rhesus monkeys with [3H]androstenedione resulted in the identification of free and conjugated [3H]estrone and free [3H]estradiol from the perfusates. In the dissected cerebral tissues, estrogens were recovered only from the hypothalamus and limbic system. The production of estrogens from androstenedione during the 40-minute perfusions in these two experiments totaled 1.58 and 2.83 nanograms.Keywords
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