PEPTIDE FORMATION MEDIATED BY HYDROGEN CYANIDE TETRAMER: A POSSIBLE PREBIOTIC PROCESS
- 1 November 1969
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 64 (3) , 1011-1015
- https://doi.org/10.1073/pnas.64.3.1011
Abstract
Chemical evolution on the primitive earth must have involved condensation of α-amino acids to peptides. Under aqueous conditions consistent with current conceptions of primordial waters, heating glycerine with the hydrogen cyanide tetramer, diaminomaleonitrile, yields dipeptide. If nitrogen was cycled through primordial waters as cyanide, peptide synthesis by stepwise tetramer-mediated condensation of α-amino acids would have been a plausible process.Keywords
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