Synthesis of a New Chitin Derivative, (1-Carboxyethyl)chitosan
- 1 August 1995
- journal article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 24 (8) , 623-624
- https://doi.org/10.1246/cl.1995.623
Abstract
A new chitin derivative, (1-carboxyethyl)chitosan, was synthesized from chitin and chitosan by the reaction with 2-chloropropionic acid, and its activation effect on canine polymorphonuclear cells (PMNs) was evaluated. The degree of substitution was increased by the repetition of the reaction, but the simultaneous N-deacetylation proceeded. N-Selective 1-carboxyethylation of chitosan was achieved by reductive N-alkylation with 2-oxopropionic acid and NaBH4.This publication has 7 references indexed in Scilit:
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